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Bio Correction Ampoule Collagen R4

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    Our Bio Correction Collagen Ampoule - the best ampoule for combination skin types - is an advanced, highly effective anti-aging treatment, equipped with plant-based stem cells and liposome technologies, in a lightweight hypoallergenic formulation suitable for sensitive skin.

    Through the naturally nourishing and rejuvenating effects of Azulene and Perilla Leaf Extract combined with DERMAFIRM’s exclusive Liposome Technology, our soothing R4 range is scientifically formulated to calm sensitive, flushed skin and helps to restore skin damaged by external stimuli.

      What it does

      -Restores skin elasticity and minimizes the appearance of wrinkles to cultivate a youthful, radiant glow

      -Protects skin from the external environment
      A dual-function ampoule, it helps to combat signs of aging while soothing tired, irritated skin

      -Collagen and peptides rejuvenate and improve skin elasticity

      -Its readily absorbing formula glides on and delivers active ingredients immediately upon application for efficiency and visible results

      Key ingredients

      Azulene - protects skin from damage by strengthening the skin barrier

      Perilla Leaf Extract - promotes collagen secretion which is known to revitalize skin and prevent signs of aging

      17 Amino Acid Complexes - due to the high absorption rate, amino acids help to boost collagen and improve elasticity, whilst leaving the skin supple and moisturized

      Peptide Complex - maintains skin health by helping cells metabolize

      Hyaluronic Acid (sodium hyaluronate) - promotes skin elasticity and moisture retention

      Adenosine - improves cell regeneration to minimize the appearance of deep wrinkles, while restoring elasticity

      Allantoin - a hypoallergenic plant extract that moisturizes and soothes the skin, while protecting the skin from irritants

      CalmYang™ - a complex extract composed of 7 plant extracts that are known to be effective in controlling anti-inflammatory and immune responses. It has a stimulating and healing influence on atopic dermatitis, skin dryness, inflammation, and scarring

      Hydrolyzed Collagen - this low molecular collagen moisturizes, improves elasticity, and minimizes the appearance of wrinkles

      How to use

      In the morning and evening after applying toner, massage 1-2 pumps of the ampoule evenly over the face. Gently pat skin to finish application.

      Full ingredients

      Water, Butylene Glycol, Glycerin, 1,2-Hexanediol, Hamamelis Virginiana (Witch Hazel) Extract, Hydrolyzed Collagen, Carbomer, Tromethamine, Hydrogenated Phosphatidylcholine, PEG-60 Hydrogenated Castor Oil, Allantoin, Ethylhexylglycerin, Aloe Barbadensis Leaf Powder, Adenosine, Disodium EDTA, Glycyrrhiza Glabra (Licorice) Root Extract, Sodium Hyaluronate, Portulaca Oleracea Extract, Fragrance, Centella Asiatica Extract, Perilla Ocymoides Leaf Extract, Sodium Guaiazulene Sulfonate, Glycine, Scutellaria Baicalensis Root Extract, Polygonum Cuspidatum Root Extract, Serine, Arginine, Camellia Sinensis Leaf Extract, Beta-Glucan, Aspartic Acid, Glutamic Acid, Leucine, Rosmarinus Officinalis (Rosemary) Leaf Extract, Chamomilla Recutita (Matricaria) Flower Extract, Alanine, Lysine, Proline, Phenylalanine, Valine, Threonine, Isoleucine, Tyrosine, Histidine, Copper Tripeptide-1, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Acetyl Hexapeptide-8, Palmitoyl Oligopeptide, Nelumbo Nucifera Leaf Extract, Tripeptide-1, Palmitoyl Pentapeptide-4, Methionine, Cysteine

      Safe ingredients promise

      Our products are clean, cruelty-free, paraben-free, and made without the use of harsh ingredients, preservatives, and artificial colors. We use eco-friendly FSC-certified paper in our packaging to support sustainable forest management and protection.

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      Our Bio Correction Collagen Ampoule - the best ampoule for combination skin types - is an advanced, highly effective anti-aging treatment, equipped with plant-based stem cells and liposome technologies, in a lightweight hypoallergenic formulation suitable for sensitive skin.

      Liposome & Exosme technology

      • Liposome technologyeffectively delivers active ingredients to the dermal layer to increase absorption and efficacy.

      • Difference between liposome & exosome : Liposome is a method of encapsulating active ingredients to reduce the size to 1/200 of pores, while exosome is a special method of extracting raw materials to maximize active ingredient delivery to the core of skin concerns.

      Key Ingredients

      • Azulene Liposome®

        Azulene Liposome®

        - Liposome encapsulates active ingredients with lipid-like ingredients to boost delivery and stability.
        - 98.5% purity Azulene powder calms redness, fortifies and prevents damaging skin.
        - Effective on redness or heated skin, used as an active ingredient of ointments for skin burns.

      • Perilla Exosome®

        Perilla Exosome®

        - Exosome : Nano-sized vesicles that work as a ‘messenger’ to deliver signals between cells. Exosomes have excellent biocompatibility resulting high delivery efficiency, stability, and superior efficacy compared to conventional extraction methods.

      • Eucalyptus Exosome®

        Eucalyptus Exosome®

        - More effective in reducing inflammatory factors, promotes cell growth and regeneration, increases collagen production compared to general eucalyptus & perilla extract (patents for moisturizing, skin soothing, anti-inflammatory, cell regeneration, and wrinkle improvement)

      • Re-peptide®


        - Copper Tripeptide-1: Also known as collagen peptide or Matrixyl. Restores lipids between skin cells gradually reducing wrinkles and helps cell regeneration for smoother skin.
        - Palmitoyl Tripeptide-1 : Helps enhance the resilience of sagging skin, promotes circulation of the skin renewing cycle.

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